Non-Surgical. Regenerative. Doctor-Led.
You May Have More Options Than You’ve Been Told
A non-surgical, regenerative approach for knee, back, joint, and muscle pain, for people who’ve been told surgery is their only option left.
Grounded in Real Science, Not Hype
Powerful
“Consistent Results” – Our treatments show a meaningfully high success rate.
Natural
“Time-Tested” – We use a combination of substances with a long history of therapeutic use, refined through modern regenerative medicine.
Proven
“Evidence-Informed” – Our approach is grounded in established science. As with any medical treatment, individual results and side effects vary.
Lasting
“Matched to the Problem” – We treat the specific tissue and mechanism driving your pain, so the approach fits the problem instead of applying one solution to every case.
Have You Tried Everything For Your Knee, Back Joint and Muscle Pain?
If you’ve already tried medication, physical therapy, cortisone shots, or a brace – and the relief never quite lasted – you’re not alone, and you’re not out of options yet.
Many people arrive at this point believing surgery is the only thing left. Sometimes it is the right choice. But before you schedule it, it may be worth finding out whether the affected tissue still has the capacity to heal on its own, with the right support.
That’s what a RenuO2 evaluation is for.
Here’s why it’s worth 30 minutes of your time
This is a non-surgical joint and muscle treatment built on regenerative medicine principles. It’s not a miracle, and it’s not for everyone – but for many patients, it has meant real, lasting relief without surgery, without opioids, and without significant downtime.
Many Patients Get Their Life Back Without Surgery
Highly Successful For Painful…
Knees
Shoulders
Low Back
Neck
TMJ
Hip
Ankle
Elbow
Wrists
And much more!
What Our Clients Are Saying
Hear directly from people who came to us after trying everything else.
After 35 years of back pain and trying just about everything, it got so bad for Nicole that life came to a halt. She eventually found Denali Medical Clinic. Listen to her story above.
“I can walk now, ride a bike now, roll over in bed now…Before you go to see a surgeon, do this, just give it a chance. It really does work.”*
Life changed instantly for Chris after being in a devastating car accident. Listen to his story.
Chris went through a devastating car accident and couldn’t walk or do any of his daily activities. Listen to his story about how 5 weeks later he was able to run and do his CrossFit workouts again.
“They’re not covering up the problem. They’re actually solving it.”*
Zac's got his life back after RenuO2 helped him recover from a degenerative bulging disc
*Results may vary based on individual user and are not guaranteed.
“Denali has changed my life for the better! It really has been such a great experience to work with them. My neck does not put restrictions on my life anymore!”*
“My experience with this clinic has been very positive. The results I have seen for my knees with RenuO2 has made it possible for me to return to many activities that I thought I had lost.”*
“Denali gave me my husband back. He had been suffering for years from a herniated disc in his lower back along with a lot of neck pain…it’s been a year or two since he’s had any ozone injections and he’s still doing awesome! He’s the strongest and healthiest he’s ever been and I have the doctors at Denali to thank for that!”*
What is RenuO2?
Your body already has the capacity to heal. RenuO2 is designed to help direct that process to where it’s needed.
It’s a precise blend – Empowered Oxygen (O3), B vitamins, Dextrose, Procaine, and Lidocaine – combining three regenerative approaches (Prolotherapy, Prolozone, and Neuroprolotherapy) into a single treatment aimed at improving circulation, calming irritated nerves, and supporting tissue repair.
Healing, directed.
Where Can it Help?
- Post-surgical recovery
- Post-surgical pain
- Osteoarthritis
- Partial ACL tears
- Meniscus tears
- Tendinitis
- Bursitis
- Disc herniation
- Bulging discs
- Spinal arthritis
- And more
Features & Benefits of Renu02
Relief That Can Start Early
Many patients notice some improvement after their very first treatment. From there, the goal is simple: get you back to living your life.
Healing, Not Just Masking
RenuO2 is designed to support your body’s own repair process rather than simply covering up pain. In our experience, it has outperformed other regenerative options like standalone cortisone or hyaluronic acid injections for many patients – though the right treatment depends on your specific condition.
A Non-Surgical Path Worth Exploring First
No opioids. No long-term reliance on prescription pain medication. Minimal downtime, so you’re not putting your life on hold to explore this option.
Built for Lasting Results
Because the treatment is designed to support repair in the underlying tissue, many patients experience relief that holds up over time. Individual results vary.
One Treatment, Many Applications- Used for osteoarthritis, ACL and meniscus tears, tendinitis, bursitis, disc herniation, bulging discs, spinal arthritis, bone-on-bone joints, frozen shoulder, bone spurs, plantar fasciitis, old injury pain, and sports injuries.
Two Goals, One Treatment-
RenuO2 is designed to stimulate tissue repair while also helping reduce inflammation in the treated area.
Built Around Your Schedule
Appointments are quick, with fast turnaround – designed to fit into your life, not take it over.
Specialized Care, Rare to Find
Ozone-based regenerative therapy is practiced by a relatively small number of physicians nationwide.
RenuO2 vs Surgery vs Cortisone
RenuO2:
What’s in RenuO2 – and Why It Works
RenuO2 is a carefully formulated blend that combines three powerful healing approaches – Prolotherapy, Prolozone Therapy, and Neuroprolotherapy – into a single treatment. Its ingredients work together as signaling molecules, waking up your body’s own repair systems where they’ve gone quiet.
The Challenge with Joints and Problem Areas
Joints, ligaments, and chronically painful areas share a common problem: poor blood supply. Without adequate circulation, these tissues are starved of the oxygen and nutrients they need to recover from injury. They stay stuck in a cycle of dysfunction – not quite healing, not quite right. RenuO2 is designed to break that cycle.
What’s Inside
- Empowered Oxygen (O3) – Ozone therapy has been shown to activate powerful cellular responses, supporting tissue repair and reducing oxidative stress at the site of injury. Your cells respond to oxygen signals in fundamental ways — it’s built into your biology.
- Vitamin B Complex — B vitamins work at the cellular level, addressing intracellular and neural inflammation and supporting healthy nerve function — essential for both pain relief and true recovery.
- Dextrose — Acts as a proliferant, triggering a mild, temporary inflammatory response that signals the body to repair and reinforce damaged tissue. It also helps tighten and stabilize ligaments through this same proliferant effect.
- Procaine & Lidocaine — A small amount of each is used — not just for temporary numbing, but for something more important: Procaine in particular helps reset overactive or misfiring nerves, reactivating their natural healing signals. This is the Neuroprolotherapy component at work.
- Additives for scar tissue and Peptides can be combined with RenuO2 for enhanced healing.
How It All Comes Together
The mild, controlled inflammation triggered by RenuO2 isn’t a side effect — it’s the point. It’s a deliberate signal to your body that says: heal here. Combined, these ingredients create a cascade of repair activity in tissue that had largely given up on healing itself.
RenuO2 doesn’t override your body’s healing ability – it reminds it where to show up.
Cortisone :
Cortisone may seem to help initially, but it comes at a cost. Generally, there’s a concern that repeated use of cortisone shots may cause deterioration of the cartilage within a joint. For this reason, doctors typically limit the number of cortisone shots into a joint and even more so in the spine. Cortisone shots carry a risk of complications, such as:
- Death of nearby bone (osteonecrosis)
- Joint infection
- Nerve damage
- Thinning of skin and soft tissue around the injection site
- Temporary flare of pain and inflammation in the joint
- Tendon weakening or rupture
- Thinning of nearby bone (osteoporosis)
- Whitening or lightening of the skin around the injection site
Surgery:
The typical knee replacement surgery can cost tens of thousands. By the time you pay your thousands in annual deductible plus your 20% co-pay, you would be paying over quite a bit, plus your time off work, risk of infection, months of rehab and on and on…
We’re not here to tell you surgery is never the right choice. Sometimes it is. But Denali Specialty Clinic offers a non-surgical option worth exploring first – one that, for many patients, means getting back to the life they love without the cost, risk, and recovery time of surgery.
Why Patients Choose Denali Specialty Clinic
Regenerative medicine clinics often use similar language: non-surgical, natural, no downtime. What matters is who’s administering the treatment and how.
Decades of experience – Dr. Earl has treated hundreds of patients using this protocol.
A real evaluation, not a sales pitch – We tell you honestly whether you’re a good candidate for RenuO2. If you’re not, we’ll say so.
FAQs
WHAT ARE THE INGREDIENTS IN RENUO2?
HOW MUCH DOES IT COST?
Our new patient consultation is $149, where we learn more about your condition and discuss your health history. The goal of the consultation is to understand your condition, evaluate whether RenuO2 may be appropriate for you, and discuss your treatment options. Most people proceed with their first treatment during their initial consultation.
For most patients, their total cost at Denali is far less compared to other routes. For example, the typical knee replacement surgery is over $55,000. By the time you pay your annual deductible plus your 20% co-pay, you could be paying around $15,000. This does not include your time off work, risk of infection, months of rehab (and that time off work), etc.
Take a look at our Treatment Comparison Chart above to help you differentiate between various options. Our clinical data shows an effectiveness rate in the high-80% range for patients treated with our RenuO2 Regeneration Package.
Our RenuO2 Regeneration Package consists of 6 treatments over a span of 12 weeks. By the end of the 12-week treatment period, many of our patients report meaningful improvement in pain and function. Pricing depends on the area; see below
- Soft Tissue (any muscle or ligaments; muscle spasms, hamstring, glutes, etc.) – $1,644
- 1 Joint (ankle, knee, hip, shoulder, elbow, wrist or single SI joint) – $2,184
- Spine & Bilateral SI Joints (ex. neck, upper back, lower back or both SI joints) – $2,580
For migraines, we offer single SPG Block treatments at $455 per treatment.
“The goal of the consultation is to understand your condition, evaluate whether RenuO2 may be appropriate for you, and discuss your treatment options.”
DOES INSURANCE COVER IT?
RenuO2 treatments are not billed to insurance, so patients are responsible for the cost of treatment. We believe in being transparent about pricing so you can understand the cost before deciding whether treatment is right for you.
We accept cash and credit cards, as well as CareCredit and HSA/FSA funds when applicable.
Schedule A Consultation
Start by finding out whether RenuO2 is right for your specific condition. A consultation is a low-risk, roughly 30-minute conversation – not a commitment to treatment.